Kathleen McGuire

Kathleen McGuire

Company: Abbvie

Job title: Principal Scientist


PTPN2/N1 Small Molecule Inhibitor, ABBV-CLS-484, Promotes Activation Of Innate Immune Cell Subsets & Enhances The Inflammatory Phenotype Of Immune Cells In Tumor-Bearing Mice 4:00 pm

PTPN2/N1 inhibition enhances macrophage and dendritic cell function in response to inflammatory signals Natural killer cell activation and cytotoxic function upon stimulation is enhanced by PTPN2/N1 inhibition Innate immune activation following PTPN2/N1 inhibition correlates with anti-tumor efficacy in miceRead more

day: Conference Day 1

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