PTPN2/N1 Small Molecule Inhibitor, ABBV-CLS-484, Promotes Activation Of Innate Immune Cell Subsets & Enhances The Inflammatory Phenotype Of Immune Cells In Tumor-Bearing Mice
Time: 4:00 pm
day: Conference Day 1
Details:
- PTPN2/N1 inhibition enhances macrophage and dendritic cell function in response to inflammatory signals
- Natural killer cell activation and cytotoxic function upon stimulation is enhanced by PTPN2/N1 inhibition
- Innate immune activation following PTPN2/N1 inhibition correlates with anti-tumor efficacy in mice
