Workshop B: Advancing Translational Models for Improving Predictive Validity Within Innate Immune System-Targeted Therapies
Time: 7:00 am
day: Conference Day 2
Details:
This workshop aims to bridge the translational gap in the development of therapies targeting the innate immune system, with a specific focus on STING & TLR receptors. Attendees will gain insights into selecting, utilizing and validating translational models for effective translation of preclinical findings into clinical success.
Overview of suitable preclinical models for evaluating STING & TLR-targeted therapies
- Reviewing the advantages and limitations of in vitro, in vivo, and ex vivo models in translational research
- Highlighting novelty in humanized and organoid models for mimicking innate immune system responses
- Bridging preclinical insights to clinical translation
Translating preclinical findings into actionable insights for clinical trial design
- Addressing challenges and strategies in extrapolating preclinical efficacy to human applications
- Integrating multiple translational models for comprehensive therapy assessment
- Incorporating advanced technologies in translational research
Utilizing imaging, omics, and molecular profiling in translational model development
- Modeling immune-tumor interactions and microenvironment complexities in vitro and in vivo
- Showcasing advancements in bioengineering approaches for enhanced translational relevance
- Validating translational models for innate immune system therapies
More speakers to be announced!
