Sean Lawler

Sean Lawler

Company: Brigham and Women’s Hospital Harvard Medical School

Job title: Associate Professor of Neurosurger

Seminars:

Speaker Q&A 4:40 pm

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day: Day Two

Investigating STING in Glioblastoma 3:50 pm

Glioblastoma is a highly immunosuppressive brain tumor, that has low intrinsic T cell infiltrates. To improve immunotherapies, local activation of immune sensing pathways such as STING may be useful, by overcoming the immunosuppressive tumor microenvironment STING is present in human GBM and mouse models, although its activity in tumor cells is very low STING is…Read more

day: Day Two

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