Kimmy Kin-Mei Leung

Kimmy Kin-Mei Leung

Company: F-star Therapeutics

Job title: Project Leader

Seminars:

Speaker Q&A 3:40 pm

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day: Day One

Second Generation STING Agonist SB11285: Improving Checkpoint Inhibitor Outcomes 3:15 pm

The STING pathway can induce the activation of tumor-resident Antigen Presenting Cells (APCs) and trafficking of CD8+ T cells to the tumor in preclinical models. Survival and local tumor shrinkage in syngeneic models were significantly enhanced when SB11285 was administered intravenously with anti-CTLA antibody or anti-PD-1 antibody, suggesting synergistic activity with concomitant STING activation. Phase…Read more

day: Day One

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