Targeting the Innate Immune Checkpoint CD47-SIRPα Axis
Time: 11:50 am
day: Innate Immune Checkpoints & Activation Pre-Focus Day
- The CD47-SIRPa axis suppresses macrophage phagocytosis and has emerged as an important innate immune checkpoint.
- There are a number of agents targeting this pathway in clinical development, including antibodies, decoy receptors and bispecifics.
- Emerging clinical data will be discussed.